Resistance to Bleomycin-Induced Lung Fibrosis in MMP-8 Deficient Mice Is Mediated by Interleukin-10

BACKGROUND: Matrix metalloproteinases (MMPs) may have pro and antifibrotic roles within the lungs, due to its ability to modulate collagen turnover and immune mediators. MMP-8 is a collagenase that also cleaves a number of cytokines and chemokines. METHODOLOGY AND PRINCIPAL FINDINGS: To evaluate its...

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Main Authors: García-Prieto, Emilio, González-López, Adrián, Cabrera, Sandra, Astudillo, Aurora, Gutiérrez-Fernández, Ana, Fanjul-Fernandez, Miriam, Batalla-Solís, Estefanía, Puente, Xose S., Fueyo, Antonio, López-Otín, Carlos, Albaiceta, Guillermo M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951918/
https://ncbi.nlm.nih.gov/pubmed/20949050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013242
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