Drosophila Porin/VDAC Affects Mitochondrial Morphology

Voltage-dependent anion channel (VDAC) has been suggested to be a mediator of mitochondrial-dependent cell death induced by Ca(2+) overload, oxidative stress and Bax-Bid activation. To confirm this hypothesis in vivo, we generated and characterized Drosophila VDAC (porin) mutants and found that Pori...

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Bibliografiske detaljer
Main Authors: Park, Jeehye, Kim, Yongsung, Choi, Sekyu, Koh, Hyongjong, Lee, Sang-Hee, Kim, Jin-Man, Chung, Jongkyeong
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951900/
https://ncbi.nlm.nih.gov/pubmed/20949033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013151
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