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Susceptibility to multiple sclerosis is associated with the proximal immunoglobulin heavy chain variable region.

15 immunoglobulin heavy chain constant (CH) and variable region (VH) polymorphisms were selected to span the entire length of the heavy chain cluster. These polymorphisms were examined in 34 sib pairs concordant for multiple sclerosis (MS) and in 23 sporadic MS patients. Allele frequencies were calc...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Walter, M A, Gibson, W T, Ebers, G C, Cox, D W
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1991
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295151/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1672695/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115128
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