Susceptibility to multiple sclerosis is associated with the proximal immunoglobulin heavy chain variable region.

15 immunoglobulin heavy chain constant (CH) and variable region (VH) polymorphisms were selected to span the entire length of the heavy chain cluster. These polymorphisms were examined in 34 sib pairs concordant for multiple sclerosis (MS) and in 23 sporadic MS patients. Allele frequencies were calc...

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Publié dans:	J Clin Invest
Auteurs principaux:	Walter, M A, Gibson, W T, Ebers, G C, Cox, D W
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1991
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295151/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1672695/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115128
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