ATF3, an adaptive-response gene, enhances TGFβ signaling and cancer-initiating cell features in breast cancer cells

The activating transcription factor 3 (ATF3) gene is induced by a variety of signals, including many of those encountered by cancer cells. We present evidence that ATF3 is induced by TGFβ in the MCF10CA1a breast cancer cells and plays an integral role for TGFβ to upregulate its target genes snail, s...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Yin, Xin, Wolford, Christopher C., Chang, Yi-Seok, McConoughey, Stephen J., Ramsey, Stephen A., Aderem, Alan, Hai, Tsonwin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Company of Biologists 2010
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951469/
https://ncbi.nlm.nih.gov/pubmed/20930144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.064915
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