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Lateral opening of a translocon upon entry of protein suggests the mechanism of insertion into membranes
The structure of the protein-translocating channel SecYEβ from Pyrococcus furiosus at 3.1-Å resolution suggests a mechanism for chaperoning transmembrane regions of a protein substrate during its lateral delivery into the lipid bilayer. Cytoplasmic segments of SecY orient the C-terminal α-helical re...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2951439/ https://ncbi.nlm.nih.gov/pubmed/20855604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012556107 |
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