The molecular defect in type IIB von Willebrand disease. Identification of four potential missense mutations within the putative GpIb binding domain.

Type IIB von Willebrand Disease (vWD) is characterized by the selective loss of large von Willebrand Factor (vWF) multimers from plasma, presumably due to their increased reactivity with platelets and subsequent clearance from the circulation. Using the PCR, one of a panel of four potential missense...

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Detalhes bibliográficos
Main Authors: Cooney, K A, Nichols, W C, Bruck, M E, Bahou, W F, Shapiro, A D, Bowie, E J, Gralnick, H R, Ginsburg, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC295141/
https://ncbi.nlm.nih.gov/pubmed/1672694
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