Exon-skipping Splice Variants of Excitatory Amino Acid Transporter-2 (EAAT2) Form Heteromeric Complexes with Full-length EAAT2

The glial transporter excitatory amino acid transporter-2 (EAAT2) is the main mediator of glutamate clearance in brain. The wild-type transporter (EAAT2wt) forms trimeric membrane complexes in which each protomer functions autonomously. Several EAAT2 variants are found in control and Alzheimer-disea...

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Detalhes bibliográficos
Main Authors: Gebhardt, Florian M., Mitrovic, Ann D., Gilbert, Daniel F., Vandenberg, Robert J., Lynch, Joseph W., Dodd, Peter R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951206/
https://ncbi.nlm.nih.gov/pubmed/20688910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.153494
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