Functional consequences of the collagen/elastin switch in vascular remodeling in hyperhomocysteinemic wild-type, eNOS(−/−), and iNOS(−/−) mice

A decrease in vascular elasticity and an increase in pulse wave velocity in hyperhomocysteinemic (HHcy) cystathionine-β-synthase heterozygote knockout (CBS(−/+)) mice has been observed. Nitric oxide (NO) is a potential regulator of matrix metalloproteinase (MMP) activity in MMP-NO-tissue inhibitor o...

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Bibliographic Details
Main Authors:	Steed, Mesia M., Tyagi, Neetu, Sen, Utpal, Schuschke, Dale A., Joshua, Irving G., Tyagi, Suresh C.
Format:	Artigo
Language:	Inglês
Published:	American Physiological Society 2010
Subjects:	Translational Physiology
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2951073/ https://ncbi.nlm.nih.gov/pubmed/20581102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00065.2010
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Functional consequences of the collagen/elastin switch in vascular remodeling in hyperhomocysteinemic wild-type, eNOS(−/−), and iNOS(−/−) mice

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