3-Deazaadenosine mitigates arterial remodeling and hypertension in hyperhomocysteinemic mice

Chronic hyperhomocysteinemia (HHcy) is an important factor in development of arterial hypertension. HHcy is associated with activation of matrix metalloproteinases (MMPs); however, it is unclear whether HHcy-dependent extracellular matrix (ECM) accumulation plays a role in arterial hypertrophy and h...

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Autori principali: Ovechkin, Alexander V, Tyagi, Neetu, Sen, Utpal, Lominadze, David, Steed, Mesia M., Moshal, Karni S., Tyagi, Suresh C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182487/
https://ncbi.nlm.nih.gov/pubmed/16815886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00543.2005
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