Functional consequences of the collagen/elastin switch in vascular remodeling in hyperhomocysteinemic wild-type, eNOS(−/−), and iNOS(−/−) mice

A decrease in vascular elasticity and an increase in pulse wave velocity in hyperhomocysteinemic (HHcy) cystathionine-β-synthase heterozygote knockout (CBS(−/+)) mice has been observed. Nitric oxide (NO) is a potential regulator of matrix metalloproteinase (MMP) activity in MMP-NO-tissue inhibitor o...

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Hlavní autoři: Steed, Mesia M., Tyagi, Neetu, Sen, Utpal, Schuschke, Dale A., Joshua, Irving G., Tyagi, Suresh C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2010
Témata:
Translational Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951073/
https://ncbi.nlm.nih.gov/pubmed/20581102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00065.2010
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