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Stretch augments TGF-β1 expression through RhoA/ROCK1/2, PTK, and PI3K in airway smooth muscle cells
Transforming growth factor-β1 (TGF-β1) expression in smooth muscle cells may play an important role in the pathogenesis of asthma. However, mechanisms that are involved in the regulation of TGF-β1 gene expression in human airway smooth muscle cells (HASMCs) remain elusive. Here, we show that mechani...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Physiological Society
2010
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2951069/ https://ncbi.nlm.nih.gov/pubmed/20511342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90628.2008 |
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