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Stretch augments TGF-β1 expression through RhoA/ROCK1/2, PTK, and PI3K in airway smooth muscle cells

Transforming growth factor-β1 (TGF-β1) expression in smooth muscle cells may play an important role in the pathogenesis of asthma. However, mechanisms that are involved in the regulation of TGF-β1 gene expression in human airway smooth muscle cells (HASMCs) remain elusive. Here, we show that mechani...

詳細記述

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書誌詳細
主要な著者: Mohamed, Junaith Shaik, Boriek, Aladin M.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951069/
https://ncbi.nlm.nih.gov/pubmed/20511342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90628.2008
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