Envelope-Modified Single-Cycle Simian Immunodeficiency Virus Selectively Enhances Antibody Responses and Partially Protects against Repeated, Low-Dose Vaginal Challenge

Immunization of rhesus macaques with strains of simian immunodeficiency virus (SIV) that are limited to a single cycle of infection elicits T-cell responses to multiple viral gene products and antibodies capable of neutralizing lab-adapted SIV, but not neutralization-resistant primary isolates of SI...

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Autori principali: Alpert, Michael D., Rahmberg, Andrew R., Neidermyer, William, Ng, Sharon K., Carville, Angela, Camp, Jeremy V., Wilson, Robert L., Piatak, Michael, Mansfield, Keith G., Li, Wenjun, Miller, Christopher J., Lifson, Jeffrey D., Kozlowski, Pamela A., Evans, David T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950576/
https://ncbi.nlm.nih.gov/pubmed/20702641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00945-10
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