Envelope-Modified Single-Cycle Simian Immunodeficiency Virus Selectively Enhances Antibody Responses and Partially Protects against Repeated, Low-Dose Vaginal Challenge

Immunization of rhesus macaques with strains of simian immunodeficiency virus (SIV) that are limited to a single cycle of infection elicits T-cell responses to multiple viral gene products and antibodies capable of neutralizing lab-adapted SIV, but not neutralization-resistant primary isolates of SI...

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Detalhes bibliográficos
Main Authors: Alpert, Michael D., Rahmberg, Andrew R., Neidermyer, William, Ng, Sharon K., Carville, Angela, Camp, Jeremy V., Wilson, Robert L., Piatak, Michael, Mansfield, Keith G., Li, Wenjun, Miller, Christopher J., Lifson, Jeffrey D., Kozlowski, Pamela A., Evans, David T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950576/
https://ncbi.nlm.nih.gov/pubmed/20702641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00945-10
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