Cooperation of tumor-derived HBx mutants and p53-249(ser) mutant in regulating cell proliferation, anchorage-independent growth and aneuploidy in a telomerase-immortalized normal human hepatocyte-derived cell line

Hepatocellular carcinoma (HCC) is a common cancer and hepatitis B virus (HBV) is a major etiological agent. Convincing epidemiological and experimental evidence also links HCC to aflatoxin, a naturally occurring mycotoxin that produces a signature p53-249(ser) mutation. Recently, we have reported th...

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Main Authors: Jiang, Weidong, Wang, Xin Wei, Unger, Tamar, Forgues, Marshonna, Kim, Jin Woo, Hussain, S. Perwez, Bowman, Elise, Spillare, Elisa A., Lipsky, Michael M., Meck, Jeanne M., Cavalli, Luciane R., Haddad, Bassem R., Harris, Curtis C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950321/
https://ncbi.nlm.nih.gov/pubmed/20017137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25118
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