Cooperation of tumor-derived HBx mutants and p53-249(ser) mutant in regulating cell proliferation, anchorage-independent growth and aneuploidy in a telomerase-immortalized normal human hepatocyte-derived cell line

Hepatocellular carcinoma (HCC) is a common cancer and hepatitis B virus (HBV) is a major etiological agent. Convincing epidemiological and experimental evidence also links HCC to aflatoxin, a naturally occurring mycotoxin that produces a signature p53-249(ser) mutation. Recently, we have reported th...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Jiang, Weidong, Wang, Xin Wei, Unger, Tamar, Forgues, Marshonna, Kim, Jin Woo, Hussain, S. Perwez, Bowman, Elise, Spillare, Elisa A., Lipsky, Michael M., Meck, Jeanne M., Cavalli, Luciane R., Haddad, Bassem R., Harris, Curtis C.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950321/
https://ncbi.nlm.nih.gov/pubmed/20017137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25118
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires