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Immortalization and transformation of human mammary epithelial cells by a tumor-derived Myc mutant
The Myc transcription factor is commonly dysregulated in many human cancers, including breast carcinomas. However, the precise role of Myc in the initiation and maintenance of malignancy is unclear. In this study we compared the ability of wild-type Myc (wt Myc) or Myc phosphorylation deficient muta...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3576819/ https://ncbi.nlm.nih.gov/pubmed/18642118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-008-0127-x |
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