Contrasting patterns of Bim induction and neuroprotection in Bim-deficient mice between hippocampus and neocortex following status epilepticus

Prolonged seizures (status epilepticus) are associated with brain region-specific regulation of apoptosis-associated signaling pathways. Bcl-2 homology domain 3-only (BH3) members of the Bcl-2 gene family are of interest as possible initiators of mitochondrial dysfunction and release of apoptogenic...

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Autori principali: Murphy, Brona M., Engel, Tobias, Paucard, Alexia, Hatazaki, Seiji, Mouri, Genshin, Tanaka, Katsuhiro, Jimenez-Mateos, Eva, Woods, Ina, Dunleavy, Mark, Tuffy, Liam, Bonner, Helena P., Meller, Robert, Simon, Roger P., Strasser, Andreas, Prehn, Jochen H.M., Henshall, David C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950266/
https://ncbi.nlm.nih.gov/pubmed/19779495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2009.134
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