Protein Evolution by Molecular Tinkering: Diversification of the Nuclear Receptor Superfamily from a Ligand-Dependent Ancestor

Understanding how protein structures and functions have diversified is a central goal in molecular evolution. Surveys of very divergent proteins from model organisms, however, are often insufficient to determine the features of ancestral proteins and to reveal the evolutionary events that yielded ex...

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Hlavní autoři: Bridgham, Jamie T., Eick, Geeta N., Larroux, Claire, Deshpande, Kirti, Harms, Michael J., Gauthier, Marie E. A., Ortlund, Eric A., Degnan, Bernard M., Thornton, Joseph W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950128/
https://ncbi.nlm.nih.gov/pubmed/20957188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000497
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