Protein Evolution by Molecular Tinkering: Diversification of the Nuclear Receptor Superfamily from a Ligand-Dependent Ancestor

Understanding how protein structures and functions have diversified is a central goal in molecular evolution. Surveys of very divergent proteins from model organisms, however, are often insufficient to determine the features of ancestral proteins and to reveal the evolutionary events that yielded ex...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bridgham, Jamie T., Eick, Geeta N., Larroux, Claire, Deshpande, Kirti, Harms, Michael J., Gauthier, Marie E. A., Ortlund, Eric A., Degnan, Bernard M., Thornton, Joseph W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2010
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950128/
https://ncbi.nlm.nih.gov/pubmed/20957188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000497
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