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The Synthetic Triterpenoid, CDDO-Me, Modulates the Proinflammatory Response to In Vivo Lipopolysaccharide Challenge

The synthetic triterpenoid, CDDO-Me, has potent antiproliferative and antioxidant properties. However, its immunomodulatory effects in the context of LPS challenge are incompletely defined. Pretreatment with oral CDDO-Me significantly improved survival following lethal-dose LPS challenge in mice. To...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Auletta, Jeffery J., Alabran, Jennifer L., Kim, Byung-Gyu, Meyer, Colin J., Letterio, John J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Mary Ann Liebert, Inc. 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950060/
https://ncbi.nlm.nih.gov/pubmed/20626291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2009.0100
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