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HUMAN DHX9 HELICASE UNWINDS TRIPLE HELICAL DNA STRUCTURES

Naturally occurring poly(purine·pyrimidine) rich regions in the human genome are prone to adopt non-canonical DNA structures such as intramolecular triplexes (i.e. H-DNA). Such structure-forming sequences are abundant and can regulate the expression of several diseases-linked genes. In addition, the...

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Detalhes bibliográficos
Main Authors: Jain, Aklank, Bacolla, Albino, Chakraborty, Prasun, Grosse, Frank, Vasquez, Karen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949957/
https://ncbi.nlm.nih.gov/pubmed/20669935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100795m
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