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WRN helicase unwinds Okazaki fragment-like hybrids in a reaction stimulated by the human DHX9 helicase
Mutations in the Werner gene promote the segmental progeroid Werner syndrome (WS) with increased genomic instability and cancer. The Werner gene encodes a DNA helicase (WRN) that can engage in direct protein–protein interactions with DHX9, also known as RNA helicase A or nuclear DNA helicase II, whi...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919725/ https://ncbi.nlm.nih.gov/pubmed/20385589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq240 |
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