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Iron mediates production of a neutrophil chemoattractant by rat hepatocytes metabolizing ethanol.

Ethanol metabolism in hepatocytes is accompanied by release of a potent lipid chemoattractant for neutrophils. Production of the factor may initiate the inflammation associated with alcoholic hepatitis. In previous studies with a cytosol system from liver, production was blocked by iron chelators as...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Principais autores: Hultcrantz, R, Bissell, D M, Roll, F J
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1991
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294987/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1985111/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114999
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