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Iron mediates production of a neutrophil chemoattractant by rat hepatocytes metabolizing ethanol.
Ethanol metabolism in hepatocytes is accompanied by release of a potent lipid chemoattractant for neutrophils. Production of the factor may initiate the inflammation associated with alcoholic hepatitis. In previous studies with a cytosol system from liver, production was blocked by iron chelators as...
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| Publicado no: | J Clin Invest |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294987/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1985111/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114999 |
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