Leukotriene B4 omega-hydroxylase in human polymorphonuclear leukocytes. Partial purification and identification as a cytochrome P-450.

Human polymorphonuclear leukocytes (PMN) not only synthesize and respond to leukotriene B4 (LTB4), but also catabolize this mediator of inflammation rapidly and specifically by omega-oxidation. To characterize the enzyme(s) responsible for omega-oxidation of LTB4, human PMN were disrupted by sonicat...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Shak, S, Goldstein, I M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1985
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424026/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4044832/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112077
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