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Leukotriene B4 omega-hydroxylase in human polymorphonuclear leukocytes. Partial purification and identification as a cytochrome P-450.

Human polymorphonuclear leukocytes (PMN) not only synthesize and respond to leukotriene B4 (LTB4), but also catabolize this mediator of inflammation rapidly and specifically by omega-oxidation. To characterize the enzyme(s) responsible for omega-oxidation of LTB4, human PMN were disrupted by sonicat...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Shak, S, Goldstein, I M
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1985
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424026/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4044832/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112077
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