Leukotriene B4 omega-hydroxylase in human polymorphonuclear leukocytes. Partial purification and identification as a cytochrome P-450.

Human polymorphonuclear leukocytes (PMN) not only synthesize and respond to leukotriene B4 (LTB4), but also catabolize this mediator of inflammation rapidly and specifically by omega-oxidation. To characterize the enzyme(s) responsible for omega-oxidation of LTB4, human PMN were disrupted by sonicat...

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Main Authors: Shak, S, Goldstein, I M
Format: Artigo
Jezik:Inglês
Izdano: 1985
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC424026/
https://ncbi.nlm.nih.gov/pubmed/4044832
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