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Only signaling modules that discriminate sharply between stimulatory and nonstimulatory inputs require basal signaling for fast cellular responses

In many types of cells, binding of molecules to their receptors enables cascades of intracellular chemical reactions to take place (signaling). However, a low level of signaling also occurs in most unstimulated cells. Such basal signaling in resting cells can have many functions, one of which is tha...

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Bibliografiske detaljer
Main Authors: Artomov, Mykyta, Kardar, Mehran, Chakraborty, Arup K.
Format: Artigo
Sprog:Inglês
Udgivet: American Institute of Physics 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949596/
https://ncbi.nlm.nih.gov/pubmed/20849190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3482813
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