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Purely stochastic binary decisions in cell signaling models without underlying deterministic bistabilities

Detection of different extracellular stimuli leading to functionally distinct outcomes is ubiquitous in cell biology, and is often mediated by differential regulation of positive and negative feedback loops that are a part of the signaling network. In some instances, these cellular responses are sti...

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Bibliografiske detaljer
Main Authors: Artyomov, Maxim N., Das, Jayajit, Kardar, Mehran, Chakraborty, Arup K.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2141890/
https://ncbi.nlm.nih.gov/pubmed/18025473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706110104
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