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Tissue Factor-Dependent Procoagulant Activity of Subtilase Cytotoxin, a Potent AB(5) Toxin Produced by Shiga Toxigenic Escherichia coli
Subtilase cytotoxin (SubAB), produced by certain virulent Shiga toxigenic Escherichia coli strains, causes hemolytic uremic syndrome-like pathology in mice, including extensive microvascular thrombosis. SubAB acts by specifically cleaving the essential endoplasmic reticulum chaperone BiP. BiP has be...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2949535/ https://ncbi.nlm.nih.gov/pubmed/20874089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/656534 |
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