Occult ovarian cancers identified at risk-reducing salpingo-oophorectomy in a prospective cohort of BRCA1/2 mutation carriers

Risk-reducing salpingo-oophorectomy (RRSO) is widely used for cancer risk reduction in BRCA1 or BRCA2 (BRCA1/2) mutation carriers. Occult ovarian/fallopian tube cancers (OOC) detected at the time of RRSO have been reported in several studies with wide variability in reported prevalence. We estimated...

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Main Authors: Domchek, Susan M., Friebel, Tara M., Garber, Judy E., Isaacs, Claudine, Matloff, Ellen, Eeles, Rosalind, Evans, D. Gareth, Rubinstein, Wendy, Singer, Christian F., Rubin, Stephen, Lynch, Henry T., Daly, Mary B., Weitzel, Jeffrey, Ganz, Patricia A., Pichert, Gabriella, Olopade, Olufunmilayo I., Tomlinson, Gail, Tung, Nadine, Blum, Joanne L., Couch, Fergus, Rebbeck, Timothy R.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949487/
https://ncbi.nlm.nih.gov/pubmed/20180014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-010-0799-x
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