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Enhancement of Virus-Specific Expansion of Transgenic CD8 T Cells in Aged Mice by Dendritic Cells

Aging is associated with a decreased CD8 T cell response to multiple antigens and to virus infection. Although both intrinsic and extrinsic factors have been shown to contribute to the decrease, the mechanisms are still largely unknown. In this study, the role of dendritic cells (DCs) in the age-ass...

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Detalhes bibliográficos
Main Authors: Jiang, Jiu, Fisher, Erin, Bennett, Andrew J., Murasko, Donna M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949465/
https://ncbi.nlm.nih.gov/pubmed/20728463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2010.08.003
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