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Enhancement of Virus-Specific Expansion of Transgenic CD8 T Cells in Aged Mice by Dendritic Cells

Aging is associated with a decreased CD8 T cell response to multiple antigens and to virus infection. Although both intrinsic and extrinsic factors have been shown to contribute to the decrease, the mechanisms are still largely unknown. In this study, the role of dendritic cells (DCs) in the age-ass...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jiang, Jiu, Fisher, Erin, Bennett, Andrew J., Murasko, Donna M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949465/
https://ncbi.nlm.nih.gov/pubmed/20728463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2010.08.003
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