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Anti-AIDS agents 84. Synthesis and anti-human immunodeficiency virus (HIV) activity of 2′-monomethyl-4-methyl- and 1′-thia-4-methyl-(3′R,4′R)-3′,4′-di-O-(S)-camphanoyl-(+)-cis-khellactone (DCK) analogs

In a continuing investigation into the pharmacophores and structure-activity relationship (SAR) of (3′R,4′R)-3′,4′-di-O-(S)-camphanoyl-(+)-cis-khellactone (DCK) as a potent anti-HIV agent, 2′-monomethyl substituted 1′-oxa, 1′-thia, 1′-sulfoxide and 1′-sulfone analogs were synthesized and evaluated f...

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Bibliografski detalji
Glavni autori: Xu, Shi-Qing, Yan, Xin, Chen, Ying, Xia, Peng, Qian, Keduo, Yu, Donglei, Xia, Yi, Yang, Zheng-Yu, Morris-Natschke, Susan L., Lee, Kuo-Hsiung
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949462/
https://ncbi.nlm.nih.gov/pubmed/20846868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.08.031
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