Development and Preclinical Studies of Broad-spectrum Anti-HIV Agent (3′R,4′R)-3-Cyanomethyl-4-methyl-3′,4′-di-O-(S)-camphanoyl-(+)-cis-khellactone (3-Cyanomethyl-4-methyl-DCK)

In prior investigation, we discovered that (3'R,4'R)-3-cyanomethyl-4-methyl-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone (4, 3-cyanomethyl-4-methyl-DCK) showed promising anti-HIV activity. In these current studies, we developed and optimized successfully a practical ten-step syn...

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Detalhes bibliográficos
Main Authors: Xie, Lan, Guo, Huan-Fang, Lu, Hong, Zhuang, Xiao-Mei, Zhang, An-Ming, Wu, Gang, Ruan, Jin-Xiu, Zhou, Ting, Yu, Donglei, Qian, Keduo, Lee, Kuo-Hsiung, Jiang, Shibo
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662438/
https://ncbi.nlm.nih.gov/pubmed/19053755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm8003009
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