Dominant negative mutations of the scavenger receptor. Native receptor inactivation by expression of truncated variants.

The bovine scavenger receptor was truncated at amino acid 266 or 310 to delete either all or part, respectively, of the collagen-like domain. The truncated receptors were inactive in the binding and internalization of acetyl (Ac) low density lipoprotein (LDL). Coexpression of truncated receptor with...

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Publié dans:	J Clin Invest
Auteurs principaux:	Dejager, S, Mietus-Snyder, M, Friera, A, Pitas, R E
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1993
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294928/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8349824/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116664
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