Dominant negative mutations of the scavenger receptor. Native receptor inactivation by expression of truncated variants.

The bovine scavenger receptor was truncated at amino acid 266 or 310 to delete either all or part, respectively, of the collagen-like domain. The truncated receptors were inactive in the binding and internalization of acetyl (Ac) low density lipoprotein (LDL). Coexpression of truncated receptor with...

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Detalles Bibliográficos

Publicado en:	J Clin Invest
Principais autores:	Dejager, S, Mietus-Snyder, M, Friera, A, Pitas, R E
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical Investigation 1993
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294928/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8349824/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116664
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