Human urinary kallidinogenase suppresses cerebral inflammation in experimental stroke and downregulates nuclear factor-κB

The purpose of this study is to investigate the possible mechanism and the neuroprotective effect of human urinary kallidinogenase (HUK) in cerebral ischemia. The mouse middle cerebral artery occlusion (MCAO) model was used. Mice were treated with HUK (20 PNAU/g per day, intravenous) or saline as co...

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Bibliografiske detaljer
Main Authors: Chen, Zhi-bin, Huang, Dan-qing, Niu, Feng-nan, Zhang, Xin, Li, Er-guang, Xu, Yun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2010
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949229/
https://ncbi.nlm.nih.gov/pubmed/20179726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.19
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