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Human urinary kallidinogenase suppresses cerebral inflammation in experimental stroke and downregulates nuclear factor-κB

The purpose of this study is to investigate the possible mechanism and the neuroprotective effect of human urinary kallidinogenase (HUK) in cerebral ischemia. The mouse middle cerebral artery occlusion (MCAO) model was used. Mice were treated with HUK (20 PNAU/g per day, intravenous) or saline as co...

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Main Authors: Chen, Zhi-bin, Huang, Dan-qing, Niu, Feng-nan, Zhang, Xin, Li, Er-guang, Xu, Yun
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949229/
https://ncbi.nlm.nih.gov/pubmed/20179726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.19
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