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Human urinary kallidinogenase suppresses cerebral inflammation in experimental stroke and downregulates nuclear factor-κB

The purpose of this study is to investigate the possible mechanism and the neuroprotective effect of human urinary kallidinogenase (HUK) in cerebral ischemia. The mouse middle cerebral artery occlusion (MCAO) model was used. Mice were treated with HUK (20 PNAU/g per day, intravenous) or saline as co...

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Detalhes bibliográficos
Main Authors: Chen, Zhi-bin, Huang, Dan-qing, Niu, Feng-nan, Zhang, Xin, Li, Er-guang, Xu, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949229/
https://ncbi.nlm.nih.gov/pubmed/20179726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.19
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