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Deficiency of PAR4 attenuates cerebral ischemia/reperfusion injury in mice

Stroke is the third leading cause of death in the USA. Antithrombotic therapy targeting platelet activation is one of the treatments for ischemic stroke. Here we investigate the role of one of the thrombin receptors, protease-activated receptor 4 (PAR4), in a mouse transient middle cerebral artery o...

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Autors principals: Mao, Yingying, Zhang, Ming, Tuma, Ronald F, Kunapuli, Satya P
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949190/
https://ncbi.nlm.nih.gov/pubmed/20087365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.283
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