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USP14 Inhibitor Attenuates Cerebral Ischemia/Reperfusion-Induced Neuronal Injury in Mice

Stroke is associated with over-production of misfolded and aggregating proteins. However, it remains largely unclear whether enhanced removal of protein aggregates following ischemic stroke is neuroprotective. Deubiquitinating enzymes (DUBs) are a large group of proteases that regulate protein degra...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Min, Jia-Wei, Lü, Lanhai, Freeling, Jessica, Martin, Doug, Wang, Hongmin
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527549/
https://ncbi.nlm.nih.gov/pubmed/28029679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13941
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