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Deficiency of PAR4 attenuates cerebral ischemia/reperfusion injury in mice

Stroke is the third leading cause of death in the USA. Antithrombotic therapy targeting platelet activation is one of the treatments for ischemic stroke. Here we investigate the role of one of the thrombin receptors, protease-activated receptor 4 (PAR4), in a mouse transient middle cerebral artery o...

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Detalhes bibliográficos
Main Authors: Mao, Yingying, Zhang, Ming, Tuma, Ronald F, Kunapuli, Satya P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949190/
https://ncbi.nlm.nih.gov/pubmed/20087365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.283
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