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Crystal Structure of the ligand-binding domain of the promiscuous EphA4 receptor reveals two distinct conformations
Eph receptors and their ephrin ligands are important mediators of cell-cell communication. They are divided in two subclasses based on their affinities for each other and on sequence conservation. Receptor-ligand binding within each subclass is fairly promiscuous, while binding cross the subclasses...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2949057/ https://ncbi.nlm.nih.gov/pubmed/20678482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.07.109 |
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