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Crystal Structure of the ligand-binding domain of the promiscuous EphA4 receptor reveals two distinct conformations
Eph receptors and their ephrin ligands are important mediators of cell-cell communication. They are divided in two subclasses based on their affinities for each other and on sequence conservation. Receptor-ligand binding within each subclass is fairly promiscuous, while binding cross the subclasses...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2949057/ https://ncbi.nlm.nih.gov/pubmed/20678482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.07.109 |
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