Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex

Ephrin (Eph) receptor tyrosine kinases fall into two subclasses (A and B) according to preferences for their ephrin ligands. All published structural studies of Eph receptor/ephrin complexes involve B-class receptors. Here, we present the crystal structures of an A-class complex between EphA2 and ep...

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Detalhes bibliográficos
Main Authors: Himanen, Juha P, Goldgur, Yehuda, Miao, Hui, Myshkin, Eugene, Guo, Hong, Buck, Matthias, Nguyen, My, Rajashankar, Kanagalaghatta R, Wang, Bingcheng, Nikolov, Dimitar B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Scientific Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727437/
https://ncbi.nlm.nih.gov/pubmed/19525919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.91
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