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Glucocorticoid-Induced TNFR-Related (GITR) Protein and Its Ligand in Antitumor Immunity: Functional Role and Therapeutic Modulation

The ability of the tumor necrosis factor receptor (TNFR) family member GITR to modulate immune responses has been the subject of multiple studies. Initially thought to be critically involved in governing functions of regulatory T cells, GITR and its ligand GITRL have meanwhile been found to modulate...

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Autori principali: Placke, Theresa, Kopp, Hans-Georg, Salih, Helmut Rainer
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948872/
https://ncbi.nlm.nih.gov/pubmed/20936139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/239083
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