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Glucocorticoid-Induced TNFR-Related (GITR) Protein and Its Ligand in Antitumor Immunity: Functional Role and Therapeutic Modulation

The ability of the tumor necrosis factor receptor (TNFR) family member GITR to modulate immune responses has been the subject of multiple studies. Initially thought to be critically involved in governing functions of regulatory T cells, GITR and its ligand GITRL have meanwhile been found to modulate...

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Detalhes bibliográficos
Main Authors: Placke, Theresa, Kopp, Hans-Georg, Salih, Helmut Rainer
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948872/
https://ncbi.nlm.nih.gov/pubmed/20936139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/239083
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