Biodistribution and dosimetry of (18)F-EF5 in cancer patients with preliminary comparison of (18)F-EF5 uptake versus EF5 binding in human glioblastoma

PURPOSE: The primary purpose of this study was to assess the biodistribution and radiation dose resulting from administration of (18)F-EF5, a lipophilic 2-nitroimidazole hypoxia marker in ten cancer patients. For three of these patients (with glioblastoma) unlabeled EF5 was additionally administered...

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Detalhes bibliográficos
Main Authors: Koch, Cameron J., Scheuermann, Joshua S., Divgi, Chaitanya, Judy, Kevin D., Kachur, Alexander V., Freifelder, Richard, Reddin, Janet S., Karp, Joel, Stubbs, James B., Hahn, Stephen M., Driesbaugh, Jason, Smith, Deborah, Prendergast, Susan, Evans, Sydney M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948639/
https://ncbi.nlm.nih.gov/pubmed/20585774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-010-1517-y
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