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Sequence-Specific Correction of Genomic Hypoxanthine-Guanine Phosphoribosyl Transferase Mutations in Lymphoblasts by Small Fragment Homologous Replacement

Oligo/polynucleotide-based gene targeting strategies provide new options for achieving sequence-specific modification of genomic DNA and have implications for the development of new therapies and transgenic animal models. One such gene modification strategy, small fragment homologous replacement (SF...

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Bibliographic Details
Main Authors: Bedayat, Babak, Abdolmohamadi, Alireza, Ye, Lin, Maurisse, Rosalie, Parsi, Hooman, Schwarz, Jennifer, Emamekhoo, Hamid, Nicklas, Janice A., O'Neill, J. Patrick, Gruenert, Dieter C.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948462/
https://ncbi.nlm.nih.gov/pubmed/19995283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/oli.2009.0205
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