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l-Arginine deprivation impairs Leishmania major-specific T-cell responses

The amino acid l-arginine plays a crucial role in the regulation of immune responses. We have recently shown that uncontrolled replication of Leishmania parasites at the site of pathology correlates with high levels of arginase activity in nonhealing leishmaniasis and that this elevated arginase act...

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Autors principals: Munder, Markus, Choi, Beak-San, Rogers, Matthew, Kropf, Pascale
Format: Artigo
Idioma:Inglês
Publicat: WILEY-VCH Verlag 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948424/
https://ncbi.nlm.nih.gov/pubmed/19637195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200839041
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