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Proteophosophoglycans Regurgitated by Leishmania-Infected Sand Flies Target the L-Arginine Metabolism of Host Macrophages to Promote Parasite Survival

All natural Leishmania infections start in the skin; however, little is known of the contribution made by the sand fly vector to the earliest events in mammalian infection, especially in inflamed skin that can rapidly kill invading parasites. During transmission sand flies regurgitate a proteophosph...

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Detalhes bibliográficos
Main Authors: Rogers, Matthew, Kropf, Pascale, Choi, Beak-San, Dillon, Rod, Podinovskaia, Maria, Bates, Paul, Müller, Ingrid
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722086/
https://ncbi.nlm.nih.gov/pubmed/19696894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000555
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